We genotyped and investigated rs1048943/ CYP1A1 in a case–control sample from eastern India, followed by its global meta-analysis using a similar protocol.
Multiple testing corrections were done by the Benjamini–Hochberg method through assessment of significance at a false discovery rate of 10%. We performed a meta-analysis of candidate associations on lung cancer, its histological subtypes and smoking status in the Indian subcontinent following PRISMA guidelines. To summarise and replicate published evidence for association with lung cancer and its subgroups. Reports of genetic association of polymorphisms with lung cancer in the Indian subcontinent are often conflicting.
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